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University of Kentucky researchers make macular degeneration breakthrough

University of Kentucky researchers make macular degeneration breakthrough
7th August 2012

Researchers from the University of Kentucky have made a major breakthrough in the fight against a form of macular degeneration known as geographic atrophy (GA).

In a new study, it is claimed that by blocking several components it is possible to prevent retinal degeneration in multiple disease models.

This represents a massive leap forward, as currently macular degeneration, including GA, is largely untreatable.

The condition is common in older adults and is one of the leading causes of blindness.

Researchers have now identified that increased activity in IL-18 and MyD88 in the eye's inflammasome is present in all patients with GA. By blocking any of these components, they maintain that it is possible to prevent blindness in any form of macular degeneration.

There is now much excitement that the discovery could lead to a potential therapy for GA.

The study coincides with the release of an investigation claiming that a new oral agent could potentially quell macular degeneration.

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