Research paves way for new treatment strategy for central nervous system

New research may have paved the way for the development of new strategies to treat diseases that affect the central nervous system, such as brain injury and epilepsy.

Scientists have been able to facilitate the movement of small therapeutic agents across the blood-brain barrier in an animal model.

By turning off P-glycoprotein, which acts as a gatekeeper in the brain and prevents drugs from reaching their intended targets, agents were able to successfully penetrate the brain.

The discovery is vital for treating central nervous system conditions, as it may allow more targeted drugs to be developed that can pass through into the brain.

Dr David Miller, leader of the team that performed the study, commented: "Many promising drugs fail because they cannot cross the blood-brain barrier sufficiently to provide a therapeutic dose to the brain.

"We hope our new strategy will have a positive impact on people with brain disorders in the future."

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