Potential risk factor identified for dementia

Potential risk factor identified for dementia

Another potential risk factor for developing dementia and, in particular, Alzheimer's disease in women has been identified.

Researchers at Tufts University have found that a hormone derived from a visceral fat called adiponectin may be a risk factor for the development of all-cause dementia and Alzheimer's in women.

Data from the study has suggested an association between insulin resistance and inflammation, hallmarks for type two diabetes and the development of dementia.

Dr Thomas M van Himbergen, author of the study, explained: "Adiponectin is a hormone derived from visceral fat, which sensitizes the body to insulin, has anti-inflammatory properties, and plays a role in the metabolism of glucose and lipids."

During the study, Dr van Himbergen measured levels of glucose, insulin and glycated albumin, as well as C reactive protein, lipoprotein associated with phospholipase A2, and adiponectin in the plasma of patients at the 19th biennial examination (1985 - 1988) of the Framingham Heart Study.

During observation, it was found that adiponectin was a largely common risk factor in women who went on to develop dementia.

Previous studies have also identified that patients with diabetes are at a greater risk of developing Alzheimer's disease and other dementias.

The chance of developing the condition is also heightened if diabetes occurs in middle age.

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