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One tablet could be better than two

11th May 2007

People with high blood pressure may be better off taking one pill rather than two if their treatment combines atorvastatin, which lowers lipids and amlodipine, which reduces blood pressure, researchers reported at the American Heart Association's 8th Scientific Forum.

A single tablet containing both medications has been found to be less costly and as effective, if not more so, in preventing problems associated with high blood pressure, such as heart attack, stroke and chest pain.

Scientists found that the addition of atorvastatin to those suffering high blood pressure resulted in a significant reduction in unfavourable outcomes.

Comparing the tablet regimes, those taking two tablets experienced 6,990 cardiovascular events, compared to 6,859 among those taking the combination single tablet.

Compliance is also thought to be easier with just one tablet, resulting in improvements to patients' health.

Timothy Smith, lead author of the study, said: "This is a novel research approach that examines the economic and clinical implications of high blood pressure and cholesterol in the real world."