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New 'wine drug' may treat age-related diseases

New 'wine drug' may treat age-related diseases
11th August 2008

A new drug may be developed from an ingredient found in red wine, which could combat the effects of age-related diseases such as Alzheimer's and type-two diabetes, according to scientists.

Sirtris, a GlaxoSmithKline company, has said that mice treated with resveratrol at middle-age and above showed an overall improvement, with positive effects on bone health, the cardiovascular system and motor function.

Researchers suggested that the drug mimicked the effects of a lower-than-usual calorie diet, which in humans is thought to be linked to certain health benefits.

Study team member Dr Peter Elliott, senior vice-president of development at Sirtris, said: "A small molecule SIRT1 activator that safely mimics the ability of dietary restriction to delay age-related diseases would be of great benefit."

Chief executive officer Dr Christoph Westphal added: "This study informs us how frailty in mice can be delayed and this knowledge could help us translate pre-clinical benefits to humans."

Last week, reported that research published in the Neurology journal had suggested the consumption of oily fish may protect the brain against memory loss and other health problems.

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