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New vaccine 'cures Alzheimer's in mice'

New vaccine 'cures Alzheimer's in mice'
20th May 2008

A new vaccine could potentially offer a cure for Alzheimer's in the future as it prevents the development of an Alzheimer's-like pathology in mice.

Developed by a team from the University of Rochester Medical Centre, the medication produced an immune response to the protein amyloid-beta peptide which causes amyloid plaques in the brains of people, with the condition.

Once treated, the mice displayed normal learning skills and functioning memory despite being genetically designed to develop an aggressive form of the disease.

Writing about the findings in Molecular Therapy, the journal of The American Society of Gene Therapy, the team noted the study shows it is possible to create a safe vaccine which can prevent Alzheimer's-related memory deficits.

"The vaccinated mice not only performed better, we found no evidence of signature amyloid plaque in their brains," they added.

Meanwhile, in related news, a new poll conducted by the Alzheimer's Research Trust has highlighted that one in four people are affected by dementia.