Scientists have discovered how the activity of proteins in the brain work differently to what had previously been assumed, which could help to unlock new treatment for Alzheimer's disease.
Research had shown there is a link between protein build-ups in the brain - known as amyloid-beta plaques - and the development of Alzheimer's. However, it was not known exactly how these proteins damaged part of the brain.
Studies have shown how a prion protein attached itself to small bits of the amyloid-beta peptides. However, findings led by Dr Witold Surewicz from the American Chemical Society revealed the prion protein also attaches to build-ups of amyloid-beta and does not break them down into smaller, toxic bits.
This revelation could help to provide a breakthrough in treating this condition, potentially by using prion protein-based compounds to combat these smaller amyloid-beta pieces from developing.
For further details, this study is published in the journal ACS Chemical Neuroscience.
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