The MS Society won a host of awards at the Association of Medical Research Charities' (AMRC) 2007 Science Communication Awards.
Its website won both the charity research online award and the overall science and communication prize.
The MS Essential on muscle spasms and stiffness won best patient information leaflet.
The charity's research publication, Research Matters, came top in the design category and was runner-up in the research report for a non-expert audience category.
The final award went to More4Me, a national programme aimed at involving MS sufferers in improving care services, which was shortlisted in the patient and public involvement category.
Lee Dunster, head of research and information at the MS Society, said: "This is fantastic news. We go to great lengths to try to make sure we communicate about our research work as clearly and effectively as possible.
"Our essentials and publications depend on input from MS experts and from volunteers, and we couldn't have achieved this without their generous contributions."
Other winners and runners-up included the Stroke Association, Breakthrough Breast Cancer, BackCare, the Parkinson's Disease Society, Research into Aging, Breast Cancer Campaign, Action Medical Research and Deafness Research UK.
The AMRC's goal is to disseminate best practice and allow charities to learn from each other's successes in the use of technology to promote awareness and involve a wider section of the community.