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Metformin and exercise for diabetes 'work better alone'

Metformin and exercise for diabetes 'work better alone'
22nd August 2011

People with type 2 diabetes, who may be using home care, are often prescribed medication metformin and exercise as ways to lower their blood sugar.

However, a new University of Alberta study found that although the two methods both lower blood sugar separately, when employed together there could be a counterproductive effect.

Normand Boule, the study author, noted that the combination of both metformin and exercise could trigger a counter regulatory response, with the body working to make sure blood sugar levels do not get too low.

"During exercise, glucagon concentrations increased in the blood (a hormone secreted by the pancreas that raises glucose levels) but when we combined exercise and metformin the glucagon levels were almost twice as elevated," explained the scientist.

In other news, diabetes and hypertension could be linked to the risk of open-angle glaucoma (OAG), research by scientists at the University of Michigan has revealed.

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