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Male HRT could pose health risks

9th August 2007

Testosterone replacement therapy could lead to increased blood pressure and make older men more liable to serious disorders, according to a new study.

A team of US researchers has investigated potential links between testosterone supplements and cardiovascular and kidney disease.

Recently, there has been an increase in the number of ageing American men taking testosterone to improve their muscle mass, bone strength, libido and general quality of life.

This is despite the fact that there is no data on the safety of the supplements.

Scientists from the University of Mississippi Medical Center's Department of Physiology and Biophysics extrapolated their findings from an animal model.

These testosterone-supplemented male rates had significantly higher blood pressure than intact rats and excreted more urinary protein.

They are presenting their findings at the Sex and Gender in Cardiovascular-Renal Physiology and Pathophysiology conference which is taking place in Austin, Texas from today until Sunday.

Radu Iliescu, Licy Yanes, Julio Sartori-Valinotti, and Jane Reckelhoff are currently testing the hypotheses that the natural decrease in testosterone brought on by ageing may affect the progression of pre-existing cardiovascular and renal disease.