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Drug development strategies target multiple sclerosis and Alzheimer's

Drug development strategies target multiple sclerosis and Alzheimer's
21st October 2011

New strategies for developing drugs to treat multiple sclerosis and Alzheimer's are being recommended by researchers at the University of Houston.

A study has discovered that two estrogen receptors could target the problems caused by Alzheimer's, multiple sclerosis, cancer and cardiovascular diseases.

Dr Jan-Ake Gustafsson, University of Houston professor and Centre for Nuclear Receptors and Cell Signaling director, stated: "We have known for some time that female sex hormones-estrogens-influence a number of functions in the body.

"Only recently we and others found that one of the estrogen receptors - ERβ - is a potential target for the treatment of Alzheimer's and other chronic diseases."

Researchers have previously claimed that estrogen patches may improve the symptoms of Alzheimer's disease in women.

In a study of 20 women who were given either an estrogen patch or a placebo, women who had estrogen patches improved their performance by 20 per cent in a range of cognitive tests.

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