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Drug 'could prevent heart failure'

Drug 'could prevent heart failure'
31st May 2011

A drug could reverse overgrown hearts, helping to prevent heart failure in individuals who may be using assisted living due to their condition.

Research published in the Proceedings of the National Academy of Sciences revealed that a potential treatment for cancer could be used to restore the function of a heart at risk of failure from high blood pressure.

Scientists at the University of Texas Southwestern Medical Center found that the drugs reversed the harmful effects of autophagy in heart muscle cells in mice.

In autophagy, cells eat their own proteins to provide resources during stressful periods.

The medication is a type of histone deacetylase (HDAC) inhibitor.

Senior author Dr Joseph Hill said: "This opens the way for a new therapeutic strategy in hypertensive heart disease, one we can test for potential to promote regression of heart disease."

Meanwhile, research published in journal PLoS One has found that long term use of a four-in-one combination pull could halve the risk of stroke and heart disease.

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