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Change in approach may better target multiple sclerosis disabilities

Change in approach may better target multiple sclerosis disabilities
27th October 2011

A new discovery could prevent physical disability associated with multiple sclerosis.

Researchers have found that if they can prevent granzyme B from entering neurons, thay can prevent the killing of neurons, which results in the brain cell death experienced by multiple sclerosis patients.

Dr Fabrizio Giuliani, principal investigator on the project, stated: "It is this loss of brain cells, in the long term, which induces disability in those with multiple sclerosis.

"This is a new drug target for multiple sclerosis that is specific for the neurodegenerative process following inflammation."

Scientists have recently managed to improve their efforts to target brain cells that cause the problems at the core of multiple sclerosis.

Following a study at the University of Rochester and the University of Buffalo, researchers have isolated and directed stem cells from the human brain to become oligodendrocytes - a type of brain cell that creates myelin.

Myelin is a fatty material that coats neurons and allows them to signal effectively.

Read about Barchester expertise in offering multiple sclerosis support.