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Bristol scientists investigate cause of Alzheimer's

Bristol scientists investigate cause of Alzheimer's
22nd November 2007

A team of scientists from Bristol University are investigating the cause of blood vessel leaks which occur in Alzheimer's sufferers.

They hope that this research will enable them to pinpoint why some people suffer from the disease and others don't.

In Alzheimer's disease an abnormal protein, amyloid, builds up in the walls of blood vessels and makes them leaky. This can potentially damage surrounding brain cells.

The research team from Bristol are primarily studying the effects of bradykinin, a solution which influences the leakiness of blood vessels.

Dr Patrick Kehoe of the Dementia Research Group at the University of Bristol said: "A better understanding of this will indicate whether treatments that target this substance will be able to reduce or prevent this damage."

The research is funded by the Alzheimer's Research Trust. Rebecca Wood comma the trust's chief executive, said that she was "excited" to see the outcome of the research which "has the potential to lead to ways to protect the brain from the ravages of Alzheimer's".

According to the Alzheimer's Research Trust there are 700,000 people in the UK with some form of dementia.

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