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Alzheimer's mice study 'provides hope'

Alzheimer's mice study 'provides hope'
11th December 2009

Delaying the ageing process in mice models could help protect them from symptoms related to Alzheimer's disease, a new study has discovered.

Research from the Salk Molecular and Cell Biology Laboratory discovered that a specific signalling cascade - Insulin-Insulin Growth Factor (IGF) - might enhance brain activity that could in turn protect against Alzheimer's.

When this signalling was reduced, mice which were genetically modified to develop Alzheimer's disease had less inflammation in the brain.

Dr Susanne Sorensen of the Alzheimer's Society responded to the testing, stating: "This interesting study identifies new avenues for drug development that target this process associated with ageing.

"Drugs take years to develop and new treatments based on this discovery may be a long way from hitting pharmacy shelves."

Dr Sorensen added that dementia research continues to be "desperately underfunded" and without further investment, new treatments will not be available to those who need it most.

Additionally, she highlighted that one million people will develop dementia in the next ten years, highlighting the need to act as soon as possible.

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