Oestrogen treatment with minimal side effects to treat osteoporosis?

Oestrogen treatment with minimal side effects to treat osteoporosis?

Researchers are attempting to develop a side effect-free oestrogen treatment for osteoporosis, which could potentially lessen the dependence of some older adults on respite care.

In a study published in journal Proceedings of the National Academy of Sciences, scientists endeavoured to separate the beneficial effects of oestrogen in bone tissue from the elements linked to serious side effects such as blood clots and breast cancer.

It is hoped that this research will lead to a more focused osteoporosis treatment with lesser side effects.

Anna Borjesson of Sahlgrenska Academy said: "This is the first study to analyse the significance of different parts of a particular type of oestrogen receptor through studies in mice. It enables us to differentiate the favourable effects of oestrogen in bone tissue from the adverse effects in other tissues."

In other news, research published in journal Nature Genetics has found that osteoporosis is due to a single mutated gene.

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