Huntington's protein structure identified

Huntington's protein structure identified

Researchers have identified the earliest structural formation of the protein which causes Huntington's disease, which could open up new research avenues for the condition.

A study, published in the Biophysical Journal, were able to see the mass and size of the mutant protein structures, along the aggregation pathway to the development of the later-stage fibrils.

Christopher Stanley of Oak Ridge National Laboratory explained how the research enabled scientists to see how the proteins change as a function of times and catch the structures in their earliest form.

"When you study several of these types of systems with different glutamines or different conditions, you begin to learn more and more about the nature of these aggregates and how they begin forming," he continued.

Meanwhile, research published in journal ACS Chemical Biology identified a new way of delivering drugs to the brain which could assist in the treatment of neurodegenerative conditions such as Huntington's and Parkinson's.

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