Gender differences in Alzheimer's disease uncovered

Gender differences in Alzheimer's disease uncovered

A new study revealed at the annual meeting of the Radiological Society of North America has found gender differences in Alzheimer's disease.

Research conducted by Dr Maria Vittoria Spampinato, associate professor of radiology at the Medical University of South Carolina in Charleston, found the pattern of gray matter loss is significantly different in men and women.

She explained the extent and distribution of regional gray matter volume loss in the brain was "strongly influenced" by gender.

The results showed that compared to male patients, the women in the study had greater atrophy in gray matter 12 months prior to their diagnosis of Alzheimer's disease, as well as at the time of their diagnosis.

Dr Spampinato said: "The female patients in our study initially had more gray matter atrophy than the male patients but over time, the men caught up."

She added the disease developed "aggressively" in men.

A team led by researchers at King's College London's Institute of Psychiatry found a molecular pathway that drive the changes seen in the brains of people with Alzheimer's disease.

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