Dundee Scientists Edge Closer to Treating Parkinson's

Dundee Scientists Edge Closer to Treating Parkinson's

Researchers at Dundee University have revealed that they are getting closer to finding an innovative way to treat Parkinson's.

The team have been mapping out exactly how the condition develops, managing to find the way in which gene mutations lead to the disease itself. It has already been learnt that the gene PARK2 translates a protein known as parkin, and it is this protein that, when activated, leads to the neurodegenerative disorder.

Dr Helen Walden at the University of Dundee said: “What we have done is work out how parkin is kept switched off, and how it is switched on. It is necessary for it to be switched off because it is only needed under certain conditions."

She added that by knowing the various steps needed for turning the gene on and off, the team can now work at each stage and figure out the mechanics behind a process that goes wrong. Add to this the revelation that there are several different stages and this widens the possibility of new ways in which we can tackle the gene mutation.

The findings have been published in the EMBO journal.

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