Could targeting inflammation treat depression?

Could targeting inflammation treat depression?

Targeting inflammation in the brain could help to treat those with depression that do not respond to standard medications.

This is the finding of a new study at Emory University, which claims to have found a treatment to inhibit inflammation.

Dr Andrew H Miller, senior author of the study, commented: "Inflammation is the body's natural response to infection or wounding. However when prolonged or excessive, inflammation can damage many parts of the body, including the brain."

The investigation follows on from previous research that suggests high levels of information are likely to reduce the likelihood of responding to treatment for people with depression.

Using infliximab, a biologic drug used to treat autoimmune and inflammatory disease, Emory scientists were able to block tumor necrosis factor, which is a molecule in inflammation shown to be elevated in depressed patients.

If confirmed in further studies, the drug could prove vital in targeting those that become unresponsive to treatment and may lead to further research on the role of inflammation in depression.

Read about support and personalised care at Barchester care homes for anyone with mental health concerns.