Compound improves chemo effectiveness

Compound improves chemo effectiveness

A new compound has been discovered which has proved successful in the treatment of a certain type of lung cancer. An international clinical trial led by scientists at Dana-Farber Cancer Institute and other institutions has revealed that the compound, selumetinib, can improve the length of survival as well as the response to treatment in those with non-small cell lung cancer (NSCLC). The study followed 87 people with NSCLC where the tumours carried a mutation of the gene KRAS, something that occurs in 20 per cent of NSCLC cases, treating some with selumetinib and others with a placebo. Those taking selumetinib had an improved response rate of 37 per cent and a survival period of 9.4 months compared to 5.2 months, while the placebo group saw no change,. "This clinical trial demonstrates that a combination of chemotherapy and selumetinib is significantly better than chemotherapy alone for this group of patients – better in terms of tumour response to therapy and in terms of survival times prior to advance of the disease," said Dr Pasi A Janne, scientific co-director of Dana-Farber's Belfer Institute for Applied Cancer Science. Find the nearest Barchester nursing home